今日上海
上海科学家首创新成果 有助提高造血干细胞移植效率 - 2018年11月22日
Scientists usher in leukemia hope
A team from Shanghai has made great progress in the understanding of how hematopoietic stem cells (HSCs) “home” to hematopoietic tissue that could lead to more effective bone marrow transplants in the future.
The findings by a group of scientists at the Chinese Academy of Sciences Shanghai institute of nutrition and health were published yesterday on the website of the academic journal Nature.
The team spent six years working on HSCs, discovering “hotspots;” niches where hematopoietic stem cells accumulate. They also discovered a previously unknown “usher cell” that interacts with the HSCs and “direct” them into the hotspots, according to team leader Dr Pan Weijun.