上海科学家首揭“刹车”分子降解机制 - 2018年11月30日

Local scientists have found a new way to break the defense mechanism of malignant tumor cells, providing a possible new way to fight cancer.

Xu Chenqi and his research team from the Chinese Academy of Sciences’ Shanghai Institute of Biochemistry and Cell Biology have found a new way that T cells interact with tumors, according to a report published in the journal Nature yesterday.

T cells, a type of white blood cell, can recognize and decompose tumor cells. Tumor cells, however, fight back. They are able to interact with a protein (PD-1) on the surface of the T cells and suppress the cells’ function.