《自然》发表中科院关于基因编辑技术RNA脱靶及其优化的研究成果 - 2019年06月13日

A new and safer solution has been worked out by local researchers to tackle with the problem of off-target RNA mutations generated by DNA base editing.
Base editing can help in treatment of rare diseases, but off-target effects bring a risk of cancer.
The study published in “Nature” this week was performed by researchers in Dr. Yang Hui's Lab at the Center for Excellence in Brain Science and Intelligence Technology, Institute of Neuroscience, Chinese Academy of Sciences (CAS) with the assistance of two other research teams led by Dr. Li Yixue and Dr. Guo Fan.