今日上海
上海科学家发现长非编码RNA物种差异加工及其功能演变 - 2020年04月08日
City scientists solve biomolecule mystery
Shanghai scientists have discovered distinct roles of a mysterious biomolecule in different species, shedding light on the terra incognita of the genomic revolution.
Long noncoding RNAs, lncRNAs, are what we call the “dark matters” of genomes. Pervasively transcribed in eukaryotic genomes, lncRNAs play important roles in gene expression. And yet their roles remain largely unknown.
The latest research found that lncRNA in orthologous genes, genes in different species that can be traced back to a common ancestor, likely have different functions. It suggested how lncRNAs work in different species and evolve with the species evolution.